Destination Guide: Explore Chicago Guide

Cleo’s Southern Cuisine

Cleo’s Southern Cuisine

Practical Information & Visitor Guide

4.4 (46 reviews)
Known For

Grandmother-inspired Southern comfort food, especially fried chicken and mac and cheese, in Chicago’s Loop.

Address
190 N Wells St, Chicago, IL 60606, Chicago, Illinois, 60606, United States of America
Hours
  • Monday: 11AM-6PM
  • Tuesday: 11AM-6PM
  • Wednesday: 11AM-6PM
  • Thursday: 11AM-6PM
  • Friday: 11AM-6PM
  • Saturday: Closed
  • Sunday: Closed
Admission & Pricing
$$ $$; no admission. Confirm current menu prices directly with the restaurant.
Visit Duration
45 to 60 minutes
Accessibility
Accessibility facilities are not listed publicly; call (773) 575-7120 to confirm step-free entry, restroom access, and wheelchair seating.

Highlights & Amenities

  • Fried chicken
  • mac and cheese
  • grandmother-inspired recipes
  • weekday lunch hours
  • Loop location
  • nearby rail access

Ideal For

Comfort Food Lovers Southern Cuisine Enthusiasts Downtown Lunch Diners Families
Style: Family Travel Food & Culinary
Audience: Families with Kids Foodies
Season: Year-round

Cleo’s Southern Cuisine is a weekday Southern-comfort-food restaurant at 190 N Wells St, Chicago, IL 60606, in the Loop’s courthouse-and-theater district. Its cooking is rooted in the memory of Cleo’s grandmother and the generous, home-style recipes associated with her kitchen, drawing downtown workers and visitors for fried chicken, mac and cheese, and a hearty midday meal near Chicago’s civic center.

What to Expect at Cleo’s Southern Cuisine

This is a focused stop for the kind of Southern food built around familiar comfort rather than elaborate presentation. Fried chicken and mac and cheese are the defining order, and the restaurant’s identity centers on fresh ingredients and family-recipe cooking. Plan it as a lunch or early-afternoon destination: the kitchen operates Monday through Friday and closes at 6 PM, making it particularly convenient for Loop office workers, jury-duty visitors, and travelers exploring the nearby theaters.

Cleo’s story is personal rather than corporate. The restaurant carries forward its namesake grandmother’s culinary memory, with the menu framed around soulful, filling food made with care. The official site also offers Cleo’s merchandise and directs diners to its newer online presence, while the North Wells address places the restaurant within easy walking distance of Daley Center, Chicago Theatre, and the Chicago Riverwalk.

  • Fried chicken: A signature Southern staple and the essential first order for diners seeking Cleo’s home-style specialty.
  • Mac and cheese: One of the restaurant’s best-known comfort dishes, pairing naturally with fried chicken for a classic Southern plate.
  • Grandmother-inspired cooking: The food honors Cleo’s grandmother through recipes and a family-kitchen approach to Southern cuisine.
  • Weekday downtown lunch: Open from 11 AM to 6 PM Monday through Friday, fitting neatly into a Loop sightseeing or workday schedule.
  • North Wells location: Set near the Daley Center, State Street shopping, Chicago Theatre, and the Riverwalk.

Cleo’s Southern Cuisine at a Glance

DetailInformation
Address190 N Wells St, Chicago, IL 60606
Neighborhood / AreaThe Loop, near Daley Center and Chicago’s theater district
Operating HoursMonday-Friday 11 AM-6 PM; Saturday-Sunday closed
Admission / Price RangeNo admission; $$ restaurant price level. Current item prices are available directly from the restaurant.
Recommended Visit Duration45 to 60 minutes
Nearest Transit / ParkingWashington/Wells for Brown, Orange, Pink and Purple Line trains; Clark/Lake for Blue, Brown, Green, Orange, Pink and Purple Lines. Paid Loop garages and limited metered street parking are nearby.
Official Website & Phonecleossoutherncuisine.com; (773) 575-7120

Visiting Tips, Getting There & Nearby Pairings

Arrive close to the 11 AM opening if you want to eat before the downtown lunch rush, especially on weekdays when nearby offices, government buildings, and courts are active. Cleo’s closes at 6 PM and does not open on weekends, so it is not a dinner or Saturday sightseeing option. For current menu details, group-order questions, and any reservation arrangements, call ahead at (773) 575-7120 or check the official website before setting out.

Washington/Wells is the most direct elevated-train stop, about a short walk west; Clark/Lake gives wider rail connections a few blocks northeast. Drivers should expect standard Loop garage rates and scarce curb parking during business hours. The published restaurant information does not detail wheelchair entry, restroom configuration, or seating clearances, so travelers using a wheelchair or stroller should phone ahead to confirm arrangements. Pair lunch with a walk past the Picasso sculpture at Daley Plaza, a performance or marquee photo at the Chicago Theatre, or the Riverwalk, each roughly 5 to 15 minutes away on foot.

Frequently Asked Questions

When is Cleo’s Southern Cuisine open, and when should I go?

Cleo’s is open Monday through Friday from 11 AM to 6 PM and is closed Saturday and Sunday. Go near opening or after the main noon rush for a more relaxed weekday meal; do not plan on a late dinner because service ends at 6 PM.

How much does it cost, and are reservations needed?

Cleo’s is a $$ restaurant, with no admission charge. Exact current menu prices and reservation policies should be confirmed directly with the restaurant, particularly for larger parties or time-sensitive downtown lunches.

How long should I budget for a meal?

Allow 45 to 60 minutes for a meal, plus extra time during the weekday lunch peak. Its location makes it easy to combine with Daley Plaza, the Chicago Theatre, or an afternoon walk to the Riverwalk.

Is Cleo’s suitable for families and guests with mobility needs?

The familiar fried chicken and mac and cheese make Cleo’s a natural choice for families who enjoy straightforward comfort food. Accessibility facilities are not listed publicly; call before arrival to discuss step-free access, table spacing, restrooms, and any stroller or wheelchair needs.

When planning your Chicago travel guide or browsing verified american restaurant in Chicago, pair this stop with standout local spots including Irving Plaza, Downtown Chicago, Bavette's Bar & Boeuf, and 312 Chicago (0.2 km away).

🏨 Find Places to Stay Nearby

Compare top hotels, apartments, and vacation rentals with live pricing & availability.

Loading interactive accommodation map…

🎟️ Top Tours & Experiences in Chicago

Book verified guided tours, skip-the-line museum tickets, and outdoor excursions with free cancellation.

GetYourGuide Verified

Explore Top Rated Activities in Chicago

Find highly-rated day trips, walking tours, boat cruises, and landmark entry passes.

Browse Experiences ↗

📍 More Places to Explore in This Destination

Discover more verified attractions, sights, and hidden gems nearby.

Data Source: google_places • Recorded check: 2026-11-03

How Our Travel Guides Are Built

📍 Explore Places

Browse destinations and place listings to build your shortlist. Follow available source links for more detail.

🕒 Check Before You Go

Hours, prices, access rules, and availability can change. Confirm time-sensitive details directly with the venue.

🧭 Plan Your Visit

Use addresses and destination guides to compare locations, then check transport and booking options for your travel dates.

Keep Exploring Destinations

Browse destination guides, practical travel information, and inspiring places for your next trip.